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The murine dialysis fistula model exhibits a senescence phenotype: pathobiological mechanisms and therapeutic potential

There is no therapy that promotes maturation and functionality of a dialysis arteriovenous fistula (AVF). The search for such therapies largely relies on evaluation of vascular responses and putative therapies in experimental AVFs. We studied an AVF in mice with chronic kidney disease (CKD). We demo...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Nath, Karl A., O’Brien, Daniel R., Croatt, Anthony J., Grande, Joseph P., Ackerman, Allan W., Nath, Meryl C., Yamada, Satsuki, Terzic, Andre, Tchkonia, Tamara, Kirkland, James L., Katusic, Zvonimir S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293292/
https://ncbi.nlm.nih.gov/pubmed/30019935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00308.2018
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