Dietary fat stimulates pancreatic cancer growth and promotes fibrosis of the tumor microenvironment through the cholecystokinin receptor

The gastrointestinal peptide cholecystokinin (CCK) is released from the duodenum in response to dietary fat to aid in digestion, and plasma CCK levels are elevated with the consumption of high-fat diets. CCK is also a trophic peptide for the pancreas and has also been shown to stimulate growth of pa...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Principais autores: Nadella, Sandeep, Burks, Julian, Al-Sabban, Abdulhameed, Inyang, Gloria, Wang, Juan, Tucker, Robin D., Zamanis, Marie E., Bukowski, William, Shivapurkar, Narayan, Smith, Jill P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293257/
https://ncbi.nlm.nih.gov/pubmed/29927319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00123.2018
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