CARMA3 Mediates Allergic Lung Inflammation in Response to Alternaria alternata

The airway epithelial cell (AEC) response to allergens helps initiate and propagate allergic inflammation in asthma. CARMA3 is a scaffold protein that mediates G protein–coupled receptor–induced NF-κB activation in airway epithelium. In this study, we demonstrate that mice with CARMA3-deficient AECs...

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Vydáno v:Am J Respir Cell Mol Biol
Hlavní autoři: Causton, Benjamin, Pardo-Saganta, Ana, Gillis, Jacob, Discipio, Katherine, Kooistra, Tristan, Rajagopal, Jayaraj, Xavier, Ramnik J., Cho, Josalyn L., Medoff, Benjamin D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293075/
https://ncbi.nlm.nih.gov/pubmed/29958012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0181OC
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