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Impact of CFTR modulation with Ivacaftor on Gut Microbiota and Intestinal Inflammation
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Next to progressive airway disease, CF is also associated with intestinal inflammation and dysbiosis. Ivacaftor, a CFTR potentiator, has improved pulmonary and nutritional status but i...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6292911/ https://ncbi.nlm.nih.gov/pubmed/30546102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36364-6 |
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