Impact of CFTR modulation with Ivacaftor on Gut Microbiota and Intestinal Inflammation

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Next to progressive airway disease, CF is also associated with intestinal inflammation and dysbiosis. Ivacaftor, a CFTR potentiator, has improved pulmonary and nutritional status but i...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Ooi, Chee Y., Syed, Saad A., Rossi, Laura, Garg, Millie, Needham, Bronwen, Avolio, Julie, Young, Kelsey, Surette, Michael G., Gonska, Tanja
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292911/
https://ncbi.nlm.nih.gov/pubmed/30546102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36364-6
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