Periods of high dengue transmission defined by rainfall do not impact efficacy of dengue vaccine in regions of endemic disease

OBJECTIVE: To evaluate the association of rainy season with overall dengue disease incidence and with the efficacy of the Sanofi Pasteur recombinant, live, attenuated, tetravalent vaccine (CYD-TDV) in two randomized, controlled multicenter phase III clinical trials in Asia and Latin America. METHODS...

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Veröffentlicht in:PLoS One
Hauptverfasser: Pasin, Chloé, Halloran, M. Elizabeth, Gilbert, Peter B., Langevin, Edith, Ochiai, R. Leon, Pitisuttithum, Punnee, Capeding, Maria Rosario, Carrasquilla, Gabriel, Frago, Carina, Cortés, Margarita, Chambonneau, Laurent, Moodie, Zoe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292612/
https://ncbi.nlm.nih.gov/pubmed/30543657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207878
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