Epitope specificity of anti-synapsin autoantibodies: Differential targeting of synapsin I domains

OBJECTIVE: To identify the specific domains of the presynaptic protein synapsin targeted by recently described autoantibodies to synapsin. METHODS: Sera of 20 and CSF of two patients with different psychiatric and neurological disorders previously tested positive for immunoglobulin (Ig)G antibodies...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mertens, Robert, Melchert, Sarah, Gitler, Daniel, Schou, Morten Brix, Saether, Sverre Georg, Vaaler, Arne, Piepgras, Johannes, Kochova, Elena, Benfenati, Fabio, Ahnert-Hilger, Gudrun, Ruprecht, Klemens, Höltje, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292584/
https://ncbi.nlm.nih.gov/pubmed/30543686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208636
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