Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) RNAi is associated with cell cycle inhibition, apoptosis, DNA damage response and drug sensitivity in breast cancer

Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) is an important susceptibility locus for nicotine addiction and lung cancer. Depletion of CHRNA5 has been associated with reduced cell viability, increased apoptosis and alterations in cellular motility in different cancers yet not in breast cancer. He...

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Udgivet i:PLoS One
Main Authors: Cingir Koker, Sahika, Jahja, Ermira, Shehwana, Huma, Keskus, Ayse Gokce, Konu, Ozlen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292578/
https://ncbi.nlm.nih.gov/pubmed/30543688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208982
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