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Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases

Degradation of carbohydrates by bacteria represents a key step in energy metabolism that can be inhibited by methylated sugars. Removal of methyl groups, which is critical for further processing, poses a biocatalytic challenge because enzymes need to overcome a high energy barrier. Our structural an...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Robb, Craig S., Reisky, Lukas, Bornscheuer, Uwe T., Hehemann, Jan-Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292453/
https://ncbi.nlm.nih.gov/pubmed/30404923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180762
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