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Novel approach to temozolomide resistance in malignant glioma: connexin43-directed therapeutics
Resistance of malignant glioma, including glioblastoma (GBM), to the chemotherapeutic temozolomide (TMZ) remains a key obstacle in treatment strategies. The gap junction protein connexin43 (Cx43) has complex roles in the establishment, progression, and persistence of malignant glioma. Recent finding...
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| Publicado no: | Curr Opin Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6292445/ https://ncbi.nlm.nih.gov/pubmed/29803991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2018.05.002 |
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