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Propofol Inhibits Cerebellar Parallel Fiber-Purkinje Cell Synaptic Transmission via Activation of Presynaptic GABA(B) Receptors in vitro in Mice
Propofol is a widely used intravenous sedative-hypnotic agent, which causes rapid and reliable loss of consciousness via activation of γ -aminobutyric acid A (GABA(A)) receptors. We previously found that propofol inhibited cerebellar Purkinje cells (PC) activity via both GABA(A) and glycine receptor...
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| Udgivet i: | Front Neurosci |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6291502/ https://ncbi.nlm.nih.gov/pubmed/30574067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00922 |
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