Characterization of the virulence of a non-RT027, non-RT078 and binary toxin-positive Clostridium difficile strain associated with severe diarrhea

The expression of the Clostridium difficile binary toxin CDT is generally observed in the RT027 (ST1) and RT078 (ST11) C. difficile isolates, which are associated with severe C. difficile infection (CDI). However, we recently reported that the non-RT027 and non-RT078 C. difficile strain LC693 (TcdA(...

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Veröffentlicht in:Emerg Microbes Infect
Hauptverfasser: Li, Chunhui, Harmanus, Céline, Zhu, Duolong, Meng, Xiujuan, Wang, Shaohui, Duan, Juping, Liu, Sidi, Fu, Chenchao, Zhou, Pengcheng, Liu, Ruisi, Wu, Anhua, Kuijper, Ed J., Smits, Wiep Klaas, Fu, Lei, Sun, Xingmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291415/
https://ncbi.nlm.nih.gov/pubmed/30542069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0211-1
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