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Robust Increases in Erythropoietin Production by the Hypoxic Fetus is a Response to Protect the Brain and Other Vital Organs

Fetal erythropoietin (EPO), in addition to regulating erythropoiesis, has also tissue protective properties based on its anti-inflammatory, anti-apoptotic, antioxidant and neurotrophic effects. Notably, EPO concentrations needed for tissue protection are 100–1 000 times higher than concentrations ne...

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Veröffentlicht in:Pediatr Res
Hauptverfasser: Teramo, Kari A., Klemetti, Miira M., Widness, John A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291371/
https://ncbi.nlm.nih.gov/pubmed/29895839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41390-018-0054-4
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