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Expression of the miR-150 tumor suppressor is restored by and synergizes with rapamycin in a human leukemia T-cell line

miR-150 functions as a tumor suppressor in malignancies of the lymphocyte lineage and its expression is significantly reduced in these cells. However, the mechanism of miR-150 repression is unknown and so are pharmacological interventions that can reverse it. Here, we report that reduced expression...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Leuk Res
Egile Nagusiak: Podshivalova, Katie, Wang, Eileen A., Hart, Traver, Salomon, Daniel R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290994/
https://ncbi.nlm.nih.gov/pubmed/30269036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2018.09.009
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