Deep sequencing of circulating exosomal microRNA allows non-invasive glioblastoma diagnosis

Exosomes are nano-sized extracellular vesicles released by many cells that contain molecules characteristic of their cell of origin, including microRNA. Exosomes released by glioblastoma cross the blood–brain barrier into the peripheral circulation and carry molecular cargo distinct to that of “free...

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Udgivet i:NPJ Precis Oncol
Main Authors: Ebrahimkhani, Saeideh, Vafaee, Fatemeh, Hallal, Susannah, Wei, Heng, Lee, Maggie Yuk T., Young, Paul E., Satgunaseelan, Laveniya, Beadnall, Heidi, Barnett, Michael H., Shivalingam, Brindha, Suter, Catherine M., Buckland, Michael E., Kaufman, Kimberley L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290767/
https://ncbi.nlm.nih.gov/pubmed/30564636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-018-0071-0
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