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Assembly of fibronectin fibrils selectively attenuates platelet-derived growth factor–induced intracellular calcium release in fibroblasts

Cellular responses to platelet-derived growth factor (PDGF) are altered in a variety of pathological conditions, including cancers, fibroses, and vascular diseases, making PDGF-induced signaling pathways important therapeutic targets. The limited success of therapies designed to impact PDGF pathways...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Farrar, Christopher S., Hocking, Denise C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290149/
https://ncbi.nlm.nih.gov/pubmed/30323067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004020
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