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Design Optimization of Tumor Vasculature-Bound Nanoparticles

Nanotherapy may constitute a promising approach to target tumors with anticancer drugs while minimizing systemic toxicity. Computational modeling can enable rapid evaluation of nanoparticle (NP) designs and numerical optimization. Here, an optimization study was performed using an existing tumor mod...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chamseddine, Ibrahim M., Frieboes, Hermann B., Kokkolaras, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290012/
https://ncbi.nlm.nih.gov/pubmed/30538267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35675-y
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