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Single-Molecule Analysis Reveals Linked Cycles Of RSC Chromatin Remodeling and Ace1p Transcription Factor Binding in Yeast

It is unknown how the dynamic binding of Transcription Factors (TF) is molecularly linked to chromatin remodeling and transcription. Using SMT, we show that the chromatin remodeler RSC speeds up the search process of the TF Ace1p for its Response Elements (RE) at the CUP1 promoter. We quantified smF...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Mehta, Gunjan D., Ball, David A., Eriksson, Peter R., Chereji, Razvan. V., Clark, David J., McNally, James G., Karpova, Tatiana S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289719/
https://ncbi.nlm.nih.gov/pubmed/30318444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.09.009
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