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Sialic Acid-Dependent Inhibition of T cells by Exosomal Ganglioside GD3 in Ovarian Tumor Microenvironments

The tumor microenvironment is rendered immunosuppressive by a variety of cellular and acellular factors, which represent potential cancer therapeutic targets. While exosomes isolated from ovarian tumor ascites fluids have been previously reported to induce a rapid and reversible T cell arrest, the f...

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Detalles Bibliográficos
Publicado en:J Immunol
Autores principales: Shenoy, Gautam N., Loyall, Jenni, Berenson, Charles S., Kelleher, Raymond J., Iyer, Vandana, Balu-Iyer, Sathy V., Odunsi, Kunle, Bankert, Richard B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289713/
https://ncbi.nlm.nih.gov/pubmed/30446565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801041
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