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Modulation of alternative splicing of trafficking genes by genome editing reveals functional consequences in muscle biology

Alternative splicing is a regulatory mechanism by which multiple mRNA isoforms are generated from single genes. Numerous genes that encode membrane trafficking proteins are alternatively spliced. However, there is limited information about the functional consequences that result from these splicing...

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Detalhes bibliográficos
Publicado no:Int J Biochem Cell Biol
Main Authors: Blue, R. Eric, Koushik, Amrita, Engels, Nichlas M., Wiedner, Hannah J., Cooper, Thomas A., Giudice, Jimena
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289647/
https://ncbi.nlm.nih.gov/pubmed/30316870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2018.10.004
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