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Hsp90 inhibitors suppress P53 phosphorylation in LPS - induced endothelial inflammation

P53 has been recently involved in the defense against inflammation. The “guardian of the genome” appears to orchestrate cellular responses against bacterial toxins, by regulating crucial pathways that orchestrate the vascular barrier functions. Indeed, an emerging body of evidence suggests that this...

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Pubblicato in:Cytokine
Autori principali: Barabutis, Nektarios, Uddin, Mohammad A., Catravas, John D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289617/
https://ncbi.nlm.nih.gov/pubmed/30420201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2018.10.020
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