Cell-Selective Pore Forming Antimicrobial Peptides of the Prodomain of Human Furin: A Conserved Aromatic/Cationic Sequence Mapping, Membrane Disruption, and Atomic-Resolution Structure and Dynamics

[Image: see text] Antimicrobial peptides are promising molecules in uprising consequences of drug-resistant bacteria. The prodomain of furin, a serine protease, expressed in all vertebrates including humans, is known to be important for physiological functions. Here, potent antimicrobial peptides we...

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Bibliographic Details
Published in:ACS Omega
Main Authors: Sinha, Sheetal, Harioudh, Munesh Kumar, Dewangan, Rikeshwer P., Ng, Wun Jern, Ghosh, Jimut Kanti, Bhattacharjya, Surajit
Format: Artigo
Language:Inglês
Published: American Chemical Society 2018
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289565/
https://ncbi.nlm.nih.gov/pubmed/30555984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01876
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