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Oncogene-induced senescence: a double edged sword in cancer

Oncogene-induced cellular senescence (OIS) is a complex program that is triggered in response to aberrant activation of oncogenic signaling. Initially, OIS was thought to be a barrier to malignant transformation because of its suppression on cell proliferation. Later studies showed that senescence i...

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Bibliografske podrobnosti
izdano v:Acta Pharmacol Sin
Main Authors: Liu, Xue-ling, Ding, Jian, Meng, Ling-hua
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289471/
https://ncbi.nlm.nih.gov/pubmed/29620049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.198
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