Berberine attenuates ischemia–reperfusion injury through inhibiting HMGB1 release and NF-κB nuclear translocation

Inflammatory damage plays an important role in cerebral ischemic pathogenesis and represents a new target for treatment of stroke. Berberine is a natural medicine with multiple beneficial biological activities. In this study, we explored the mechanisms underlying the neuroprotective action of berber...

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Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Zhu, Jun-rong, Lu, Hai-dan, Guo, Chao, Fang, Wei-rong, Zhao, Hong-dong, Zhou, Jun-shan, Wang, Feng, Zhao, Yan-li, Li, Yun-man, Zhang, Ying-dong, Yang, Chang-qing, Sun, Jian-guo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289370/
https://ncbi.nlm.nih.gov/pubmed/30266998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0160-1
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