Delivery of mitochondriotropic doxorubicin derivatives using self-assembling hyaluronic acid nanocarriers in doxorubicin-resistant breast cancer

Breast cancer is the leading cause of cancer-related death for women, and multidrug resistance (MDR) is the major obstacle faced by chemotherapy for breast cancer. We have previously synthesized a doxorubicin (DOX) derivative by conjugating DOX with triphenylphosphonium (TPP) to achieve mitochondria...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Liu, Hui-na, Guo, Ning-ning, Guo, Wang-wei, Huang-Fu, Ming-yi, Vakili, Mohammad Reza, Chen, Jie-jian, Xu, Wen-hong, Wei, Qi-chun, Han, Min, Lavasanifar, Afsaneh, Gao, Jian-qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289358/
https://ncbi.nlm.nih.gov/pubmed/29849132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2018.9
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