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Manipulation-free cultures of human iPSC-derived cardiomyocytes offer a novel screening method for cardiotoxicity

Induced pluripotent stem cell (iPSC)-based cardiac regenerative medicine requires the efficient generation, structural soundness and proper functioning of mature cardiomyocytes, derived from the patient's somatic cells. The most important functional property of cardiomyocytes is the ability to...

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Détails bibliographiques
Publié dans:Acta Pharmacol Sin
Auteurs principaux: Rajasingh, Sheeja, Isai, Dona Greta, Samanta, Saheli, Zhou, Zhi-gang, Dawn, Buddhadeb, Kinsey, William H, Czirok, Andras, Rajasingh, Johnson
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289337/
https://ncbi.nlm.nih.gov/pubmed/29620051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.183
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