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Transferrin receptor-targeted HMSN for sorafenib delivery in refractory differentiated thyroid cancer therapy

BACKGROUND: Thyroid cancer becomes the most common endocrine cancer with the greatest growing incidence in this decade. Sorafenib is a multikinase inhibitor for the treatment of progressive radioactive iodine-refractory differentiated thyroid cancer (DTC), while the off-target toxicity effect is usu...

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Publicat a:Int J Nanomedicine
Autors principals: Ke, You, Xiang, Cheng
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289230/
https://ncbi.nlm.nih.gov/pubmed/30584304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S187240
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