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Spatially Resolving the Condensing Effect of Cholesterol in Lipid Bilayers

We study the effect of cholesterol on the structure of dipalmitoylphosphatidylcholine phospholipid bilayers. Using extensive molecular dynamics computer simulations at atomistic resolution, we observe and quantify several structural changes upon increasing cholesterol content that are collectively k...

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Detalles Bibliográficos
Publicado en:Biophys J
Autores principales: Leeb, Felix, Maibaum, Lutz
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289096/
https://ncbi.nlm.nih.gov/pubmed/30447996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.10.024
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