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Dexmedetomidine expands monocytic myeloid-derived suppressor cells and promotes tumour metastasis after lung cancer surgery

BACKGROUND: Dexmedetomidine (DEX) has been reported to promote tumour metastases. However the underlying mechanisms remain unclear. The purpose of this study was to investigate whether DEX promotes tumour metastasis by inducing myeloid-derived suppressor cells (MDSC) in the context of surgery. METHO...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Su, Xiaosan, Fan, Yaodong, Yang, Liu, Huang, Jie, Qiao, Fei, Fang, Yu, Wang, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288950/
https://ncbi.nlm.nih.gov/pubmed/30537999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1727-9
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