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Curcumin inhibits proliferation, migration, invasion and promotes apoptosis of retinoblastoma cell lines through modulation of miR-99a and JAK/STAT pathway

BACKGROUND: Curcumin, a primary active ingredient extracted from the Curcuma longa, has been recently identified as a potential anti-tumor agent in multiple kinds of cancers. However, the effect of curcumin on retinoblastoma (Rb) is still unclear. Therefore, we attempted to reveal the functional imp...

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Publié dans:BMC Cancer
Auteurs principaux: Li, Yaping, Sun, Weixuan, Han, Ning, Zou, Ying, Yin, Dexin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288931/
https://ncbi.nlm.nih.gov/pubmed/30526546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5130-y
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