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Mean-Variance QTL Mapping Identifies Novel QTL for Circadian Activity and Exploratory Behavior in Mice

We illustrate, through two case studies, that “mean-variance QTL mapping”—QTL mapping that models effects on the mean and the variance simultaneously—can discover QTL that traditional interval mapping cannot. Mean-variance QTL mapping is based on the double generalized linear model, which extends th...

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Podrobná bibliografie
Vydáno v:G3 (Bethesda)
Hlavní autoři: Corty, Robert W., Kumar, Vivek, Tarantino, Lisa M., Takahashi, Joseph S., Valdar, William
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288835/
https://ncbi.nlm.nih.gov/pubmed/30389793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200194
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