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Fe(III)-Catalyzed Bicyclization of Yne-Allenones With Indoles for the Atom-Economic Synthesis of 3-Indolyl Cyclobutarenes

A new Fe(III)-catalyzed bicyclization reaction of yne-allenones with indoles has been established, enabling the direct construction of cyclobuta[a]naphthalen-4-ols with an all-carbon quaternary center in good to excellent yields. This reaction was performed by using low-cost FeCl(3) as the catalyst...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Li, Heng, Hao, Wen-Juan, Li, Guigen, Tu, Shu-Jiang, Jiang, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288644/
https://ncbi.nlm.nih.gov/pubmed/30564570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00599
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