Defining HIV-1 Envelope N-Glycan Microdomains through Site-Specific Heterogeneity Profiles

The HIV-1 envelope (Env) glycans shield the surface of Env from the immune system and form integral interactions important for a functional Env. To understand how individual N-glycosylation sites (NGS) coordinate to form a dynamic shield and evade the immune system through mutations, we tracked 20 N...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Hargett, Audra A., Wei, Qing, Knoppova, Barbora, Hall, Stacy, Huang, Zhi-Qiang, Prakash, Amol, Green, Todd J., Moldoveanu, Zina, Raska, Milan, Novak, Jan, Renfrow, Matthew B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Structure and Assembly
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288332/
https://ncbi.nlm.nih.gov/pubmed/30305355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01177-18
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