Novel Cre-Expressing Mouse Strains Permitting to Selectively Track and Edit Type 1 Conventional Dendritic Cells Facilitate Disentangling Their Complexity in vivo

Type 1 conventional DCs (cDC1) excel in the cross-priming of CD8(+) T cells, which is crucial for orchestrating efficient immune responses against viruses or tumors. However, our understanding of their physiological functions and molecular regulation has been limited by the lack of proper mutant mou...

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Pubblicato in:Front Immunol
Autori principali: Mattiuz, Raphaël, Wohn, Christian, Ghilas, Sonia, Ambrosini, Marc, Alexandre, Yannick O., Sanchez, Cindy, Fries, Anissa, Vu Manh, Thien-Phong, Malissen, Bernard, Dalod, Marc, Crozat, Karine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288293/
https://ncbi.nlm.nih.gov/pubmed/30564233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02805
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