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Limbal epithelial stem cell activity and corneal epithelial cell cycle parameters in adult and aging mice

Limbal epithelial stem cells (LESCs) are believed to be responsible for corneal epithelial maintenance and repair after injury, but their activity has never been properly quantified in aging or wounded eyes. In this study, labelling with thymidine analogues, 5-iodo-2′-deoxyuridine (IdU), 5-chloro-2′...

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Détails bibliographiques
Publié dans:Stem Cell Res
Auteurs principaux: Sagga, Nada, Kuffová, Lucia, Vargesson, Neil, Erskine, Lynda, Collinson, J. Martin
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288239/
https://ncbi.nlm.nih.gov/pubmed/30439642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2018.11.001
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