Gasdermin E Does Not Limit Apoptotic Cell Disassembly by Promoting Early Onset of Secondary Necrosis in Jurkat T Cells and THP-1 Monocytes

During the progression of necroptosis and pyroptosis, the plasma membrane will become permeabilized through the activation of mixed lineage kinase domain like pseudokinase (MLKL) or gasdermin D (GSDMD), respectively. Recently, the progression of apoptotic cells into secondary necrotic cells followin...

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Udgivet i:Front Immunol
Main Authors: Tixeira, Rochelle, Shi, Bo, Parkes, Michael A. F., Hodge, Amy L., Caruso, Sarah, Hulett, Mark D., Baxter, Amy A., Phan, Thanh Kha, Poon, Ivan K. H.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288192/
https://ncbi.nlm.nih.gov/pubmed/30564238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02842
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