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Ketamine and selective activation of parvalbumin interneurons inhibit stress-induced dendritic spine elimination

Stress is a major risk factor for the onset of many psychiatric diseases. In rodent models, chronic stress induces depression and impairs excitatory neurotransmission. However, little is known about the effect of stress on synaptic circuitry during the development of behavioral symptoms. Using two-p...

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Detalles Bibliográficos
Publicado en:Transl Psychiatry
Main Authors: Ng, Lhotse Hei Lui, Huang, Yuhua, Han, Lei, Chang, Raymond Chuen-Chung, Chan, Ying Shing, Lai, Cora Sau Wan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288154/
https://ncbi.nlm.nih.gov/pubmed/30531859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0321-5
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