Role of individual S4 segments in gating of Ca(v)3.1 T-type calcium channel by voltage

Contributions of voltage sensing S4 segments in domains I – IV of Ca(V)3.1 channel to channel activation were analyzed. Neutralization of the uppermost charge in individual S4 segments by exchange of arginine for cysteine was employed. Mutant channels with single exchange in domains I – IV, in two a...

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Detalles Bibliográficos
Publicado en:Channels (Austin)
Autores principales: Jurkovicova-Tarabova, Bohumila, Mackova, Katarina, Moravcikova, Lucia, Karmazinova, Maria, Lacinova, Lubica
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
Materias:
Brief Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287678/
https://ncbi.nlm.nih.gov/pubmed/30403912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2018.1543520
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