A Pathophysiologic Approach Combining Genetics and Insulin Resistance to Predict the Severity of Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) is a complex disease dictated by both genetic and environmental factors. While insulin resistance (IR) is a key pathogenic driver, two common genetic variants in patatin‐like phospholipase domain containing 3 (PNPLA3) and transmembrane 6 superfamily member 2...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Danford, Christopher J., Connelly, Margery A., Shalaurova, Irina, Kim, Misung, Herman, Mark A., Nasser, Imad, Otvos, James D., Afdhal, Nezam H., Jiang, Z. Gordon, Lai, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287585/
https://ncbi.nlm.nih.gov/pubmed/30556036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1267
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