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Hantavirus-Driven PD-L1/PD-L2 Upregulation: An Imperfect Viral Immune Evasion Mechanism

Viruses often subvert antiviral immune responses by taking advantage of inhibitory immune signaling. We investigated if hantaviruses use this strategy. Hantaviruses cause viral hemorrhagic fever (VHF) which is associated with strong immune activation resulting in vigorous CD8+ T cell responses. Surp...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Raftery, Martin J., Abdelaziz, Mohammed O., Hofmann, Jörg, Schönrich, Günther
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287426/
https://ncbi.nlm.nih.gov/pubmed/30559738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02560
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