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Apoptosis Induction via ATM Phosphorylation, Cell Cycle Arrest, and ER Stress by Goniothalamin and Chemodrugs Combined Effects on Breast Cancer-Derived MDA-MB-231 Cells

Goniothalamin (GTN), a styryl-lactone, exhibits inhibitory effects on many kinds of cancer cells in vitro. The objectives of this study were to investigate the anticancer activities of GTN and molecular signaling pathways associated with cell death in human breast cancer MDA-MB-231 cell line. GTN in...

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Bibliografische gegevens
Gepubliceerd in:Biomed Res Int
Hoofdauteurs: Khaw-on, Patompong, Pompimon, Wilart, Banjerdpongchai, Ratana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287143/
https://ncbi.nlm.nih.gov/pubmed/30598998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7049053
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