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CAR T Cell Therapy of Non-hematopoietic Malignancies: Detours on the Road to Clinical Success
Chimeric antigen receptor (CAR)-engineered T cells represent a breakthrough in personalized medicine. In this strategy, a patient's own T lymphocytes are genetically reprogrammed to encode a synthetic receptor that binds a tumor antigen, allowing T cells to recognize and kill antigen-expressing...
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Publicado no: | Front Immunol |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6287001/ https://ncbi.nlm.nih.gov/pubmed/30559740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02740 |
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