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Tau’s Three-Repeat Domain and EFhd2 Co-incubation Leads to Increased Thioflavin Signal

Aggregation of the protein tau is a pathological hallmark of Alzheimer’s disease (AD) and related disorders. However, the molecular mechanisms that lead to tau protein aggregation are still unclear. Previously, we showed that EFhd2 protein is associated with pathological aggregated forms of tau in A...

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Vydáno v:Front Neurosci
Hlavní autoři: Vega, Irving E., Sutter, Alexandra, Parks, Luke, Umstead, Andrew, Ivanova, Magdalena I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286997/
https://ncbi.nlm.nih.gov/pubmed/30559642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00879
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