Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy

Chagas disease is caused by infection with the protozoan Trypanosoma cruzi and affects over 8 million people worldwide. In spite of a powerful innate and adaptive immune response in acute infection, the parasite evades eradication, leading to a chronic persistent infection with low parasitism. Chron...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Chevillard, Christophe, Nunes, João Paulo Silva, Frade, Amanda Farage, Almeida, Rafael Ribeiro, Pandey, Ramendra Pati, Nascimento, Marilda Savóia, Kalil, Jorge, Cunha-Neto, Edecio
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286977/
https://ncbi.nlm.nih.gov/pubmed/30559742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02791
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