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Genotype Is Associated to the Degree of Virilization in Patients With Classic Congenital Adrenal Hyperplasia

Background: Molecular defects of CYP21A2 consistently decrease 21-hydroxylase activity and result in a variable expression of disease severity in patients with congenital adrenal hyperplasia (CAH). Aim: The genotype and biochemical findings were examined in an attempt to reveal any association to th...

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Détails bibliographiques
Publié dans:Front Endocrinol (Lausanne)
Auteurs principaux: Neocleous, Vassos, Fanis, Pavlos, Phylactou, Leonidas A., Skordis, Nicos
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286958/
https://ncbi.nlm.nih.gov/pubmed/30559721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00733
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