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Egr-1 is involved in coronary microembolization-induced myocardial injury via Bim/Beclin-1 pathway-mediated autophagy inhibition and apoptosis activation

Coronary microembolization (CME) substantially reduces the clinical benefits of myocardial reperfusion therapy. Autophagy and apoptosis participate in the pathophysiological processes of almost all cardiovascular diseases, including CME-induced myocardial injury, but the precise underlying mechanism...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Wang, Xian-tao, Wu, Xiao-dan, Lu, Yuan-xi, Sun, Yu-han, Zhu, Han-hua, Liang, Jia-bao, He, Wen-kai, Li, Lang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286823/
https://ncbi.nlm.nih.gov/pubmed/30391937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101616
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