Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice

BACKGROUND: Mesenchymal stem/stromal cells (MSCs) are a promising tool for cell-based therapies in the treatment of tissue injury. The stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor 4 (CXCR4) axis plays a significant role in directing MSC homing to sites of injury. However in vivo MSC...

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Udgivet i:PeerJ
Main Authors: Jin, Wang, Liang, Xiaowen, Brooks, Anastasia, Futrega, Kathryn, Liu, Xin, Doran, Michael R., Simpson, Matthew J., Roberts, Michael S., Wang, Haolu
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2018
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286806/
https://ncbi.nlm.nih.gov/pubmed/30564525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.6072
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