A trial of P2Y(12) receptor inhibition with prasugrel identifies a potentially distinct endotype of patients with aspirin-exacerbated respiratory disease.

BACKGROUND: Aspirin-exacerbated respiratory disease (AERD) is characterized by asthma, recurrent nasal polyposis, and respiratory reactions upon ingestion of cyclooxygenase-1 inhibitors. Increased numbers of platelet-leukocyte aggregates are present in the sinus tissue and blood of patients with AER...

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Vydáno v:J Allergy Clin Immunol
Hlavní autoři: Laidlaw, Tanya M., Cahill, Katherine N., Cardet, Juan Carlos, Murphy, Katherine, Cui, Jing, Dioneda, Brittney, Kothari, Parul, Raby, Benjamin A., Israel, Elliot, Boyce, Joshua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286686/
https://ncbi.nlm.nih.gov/pubmed/29890239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.06.001
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