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IFN‐λ4 inhibits HIV infection of macrophages through signalling of IFN‐λR1/IL‐10R2 receptor complex

The recently discovered IFN‐λ4 has been found to have antiviral activity against several viruses. However, it's unknown whether IFN‐λ4 can inhibit HIV infection. Here, we show that IFN‐λ4 could suppress HIV infection of macrophages. This IFN‐λ4‐mediated HIV inhibition was compromised by the ant...

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Detalhes bibliográficos
Publicado no:Scand J Immunol
Main Authors: Su, Qi‐Jian, Wang, Xu, Zhou, Run‐Hong, Guo, Le, Liu, Hang, Li, Jie‐Liang, Ho, Wen‐Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286684/
https://ncbi.nlm.nih.gov/pubmed/30247785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/sji.12717
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