Day-Night Oscillation of Atrogin1 and Timing-Dependent Preventive Effect of Weight-Bearing on Muscle Atrophy

BACKGROUND: Atrogin1, which is one of the key genes for the promotion of muscle atrophy, exhibits day-night variation. However, its mechanism and the role of its day-night variation are largely unknown in a muscle atrophic context. METHODS: The mice were induced a muscle atrophy by hindlimb-unloadin...

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Gepubliceerd in:EBioMedicine
Hoofdauteurs: Aoyama, Shinya, Kojima, Shuichi, Sasaki, Keisuke, Ishikawa, Ryosuke, Tanaka, Mizuho, Shimoda, Takeru, Hattori, Yuta, Aoki, Natsumi, Takahashi, Kengo, Hirooka, Rina, Takizawa, Miku, Haraguchi, Atsushi, Shibata, Shigenobu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2018
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Research paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286653/
https://ncbi.nlm.nih.gov/pubmed/30391495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.057
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