Ponatinib induces a sustained deep molecular response in a chronic myeloid leukaemia patient with an early relapse with a T315I mutation following allogeneic hematopoietic stem cell transplantation: a case report

BACKGROUND: Atypical BCR-ABL1 transcripts are detected in less than 5% of patients diagnosed with chronic myeloid leukaemia (CML), of which e19a2 is the most frequently observed, with breakpoints in the micro breakpoint cluster region (μ-BCR) and coding for the p230 BCR-ABL1 protein. p230 CML is ass...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Cerveira, Nuno, Ferreira, Rosa Branca, Bizarro, Susana, Correia, Cecília, Torres, Lurdes, Lisboa, Susana, Vieira, Joana, Santos, Rui, Campilho, Fernando, Pinho Vaz, Carlos, Leite, Luís, Teixeira, Manuel R., Campos, António
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286606/
https://ncbi.nlm.nih.gov/pubmed/30526517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5100-4
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